Bcl-2/Mcl-1-IN-4
CAT:
804-HY-159513
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Bcl-2/Mcl-1-IN-4
- UNSPSC Description: Bcl-2/Mcl-1-IN-4 (compound 20) is a dual inhibitor targeting Bcl-2 (Ki=0.49 μM) and Mcl-1 (Ki=0.51 μM). Bcl-2/Mcl-1-IN-4 significantly inhibits cancer cell proliferation and effectively induces apoptosis in U937 cells. Bcl-2/Mcl-1-IN-4 can be used in cancer research[1].
- Target Antigen: Apoptosis; Bcl-2 Family
- Type: Reference compound
- Related Pathways: Apoptosis
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/bcl-2-mcl-1-in-4.html
- Smiles: O=C(NS(=O)(C1=CC=C([N+]([O-])=O)C=C1)=O)[C@@H](NC(CN2C(/C(SC2=O)=C/C3=CC=C(C4=CC=C(C)C=C4)C=C3)=O)=O)CC5=CC=C(Br)C=C5
- Molecular Weight: 763.63
- References & Citations: [1]Jiabing Long, et al. "Discovery and development of thiazolidine-2, 4-dione derivatives as Bcl-2/Mcl-1 dual inhibitors." Bioorganic Chemistry (2024): 107687.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported