MCL-1/BCL-2-IN-4

MCL-1/BCL-2-IN-4

• CAS Number: 2163793-56-2
• UNSPSC Description: MCL-1/BCL-2-IN-4 (Compound 7) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor[1].
• Target Antigen: Bcl-2 Family
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mcl-1-bcl-2-in-4.html
• Solubility: DMSO : 20.83 mg/mL (ultrasonic)
• Smiles: O=C(O)CCCCC(NCCN(C(C1=CC=C(SC2=CC=C(Br)C=C2)C3=CC=CC4=C13)=O)C4=O)=O
• Molecular Weight: 555.44
• References & Citations: [1]Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported