GOT1 Recombinant Mouse Monoclonal Antibody [A2D6-R]

• Description:

  Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

• Product Name Alternative:

  AATC_HUMAN antibody Aspartate aminotransferase 1 antibody Aspartate aminotransferase antibody Aspartate aminotransferase cytoplasmic antibody Aspartate aminotransferase cytosolic antibody ASTQTL1 antibody cAspAT antibody cCAT antibody cysteine aminotransferase, cytoplasmic antibody cysteine transaminase, cytoplasmic antibody cytoplasmic antibody ec 2.6.1.1 antibody GIG 18 antibody GIG18 antibody Glutamate oxaloacetate transaminase 1 antibody Glutamate oxaloacetate transaminase soluble antibody Glutamic oxaloacetic transaminase 1 soluble antibody GOT 1 antibody GOT1 antibody Growth inhibiting protein 18 antibody SGOT antibody Transaminase A antibody

• Abbreviation:

  GOT1

• Swiss Prot:

  P17174 Human, P05201 Mouse, P13221 Rat

• Cellular Locus:

  Cytoplasm.

• Host:

  Mouse

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within Human GOT1 aa 16-211 / 413.

• Isotype:

  IgG1

• Clone:

  A2D6-R

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Mouse monoclonal Antibody

• Applications:

  WB

• Positive Control:

  HeLa cell lysate, K-562 cell lysate, HL-60 cell lysate, Caco-2 cell lysate, human liver tissue lysate, mouse liver tissue lysate, mouse heart tissue lysate, rat liver tissue lysate, rat heart tissue lysate.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 46 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3