Harmalol

• Description:

  Harmalol is a β-carbazine alkaloid with anticancer activity. Harmalol binds and interacts with several natural and synthetic nucleic acids of different motifs, including DNA and RNA. In addition, harmalol has an apoptosis-inducing effect on human hepatoma cells in vitro[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H312-H332

• Target:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/harmalol.html

• Smiles:

  CC1=NCCC2=C1NC3=C2C=CC(O)=C3

• Molecular Formula:

  C12H12N2O

• Molecular Weight:

  200.24

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

• References & Citations:

  [1]Sarkar S, et al. Therapeutic role of harmalol targeting nucleic acids: Biophysical perspective and in vitro cytotoxicity[J]. Mini reviews in medicinal chemistry, 2018, 18 (19) : 1624-1639.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  525-57-5