Harmalol

• Description :

  Harmalol is a β-carbazine alkaloid with anticancer activity. Harmalol binds and interacts with several natural and synthetic nucleic acids of different motifs, including DNA and RNA. In addition, harmalol has an apoptosis-inducing effect on human hepatoma cells in vitro[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H312-H332

• Target :

  Apoptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/harmalol.html

• Smiles :

  CC1=NCCC2=C1NC3=C2C=CC(O)=C3

• Molecular Formula :

  C12H12N2O

• Molecular Weight :

  200.24

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

• References & Citations :

  [1]Sarkar S, et al. Therapeutic role of harmalol targeting nucleic acids: Biophysical perspective and in vitro cytotoxicity[J]. Mini reviews in medicinal chemistry, 2018, 18 (19) : 1624-1639.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [525-57-5]