Harmol (Standard)

• Description :

  Harmol (Standard) is the analytical standard of Harmol (HY-107811) . This product is intended for research and analytical applications. Harmol hydrochloride is an orally active β-carboline alkaloid. Harmol hydrochloride is a TFEB activator and monoamine oxidase inhibitor. Harmol can induce cell mitosis, Autophagy and Apoptosis. Harmol promotes the degradation of α-synuclein by regulating the autophagy-lysosomal pathway. Harmol has anti-tumor, anti-depressant and anti-aging activities. Harmol improves motor impairment in a mouse Parkinson's disease model[1][2][3][4].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Autophagy; Mitosis; Monoamine Oxidase; Reference Standards; α-synuclein

• Type :

  Reference Standards

• Related Pathways :

  Apoptosis; Autophagy; Neuronal Signaling; Others

• Field of Research :

  Cancer; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/harmol-standard.html

• Smiles :

  OC1=CC2=C(C=C1)C3=C(C(C)=NC=C3)N2

• Molecular Formula :

  C12H10N2O

• Molecular Weight :

  198.22

• References & Citations :

  [1]Blei F, et al. Simultaneous Production of Psilocybin and a Cocktail of β-Carboline Monoamine Oxidase Inhibitors in "Magic" Mushrooms. Chemistry. 2020 Jan 13;26 (3) :729-734.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [487-03-6]