(E)-2-Hydroxycinnamaldehyde

• UNSPSC Description:

  (E)-2-Hydroxycinnamaldehyde is an aldehyde that can be separated from the stem bark of cinnamon. (E)-2-Hydroxycinnamaldehyde inhibits cell proliferation and induces apoptosis by inhibiting signal transduction of STAT3 and reactive oxygen species production. (E)-2-Hydroxycinnamaldehyde has antitumor activity[1].

• Target Antigen:

  Apoptosis; Reactive Oxygen Species; STAT

• Type:

  Natural Products

• Related Pathways:

  Apoptosis;Immunology/Inflammation;JAK/STAT Signaling;Metabolic Enzyme/Protease;NF-κB;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/e-2-hydroxycinnamaldehyde.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C/C=C/C1=C(C=CC=C1)O

• Molecular Weight:

  148.16

• References & Citations:

  [1]Yoon YJ, et al. 2'-Hydroxycinnamaldehyde inhibits proliferation and induces apoptosis via signal transducer and activator of transcription 3 inactivation and reactive oxygen species generation. Cancer Sci. 2019 Jan;110(1):366-378.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  60125-23-7