(E) -2-Hydroxycinnamaldehyde

• Description:

  (E) -2-Hydroxycinnamaldehyde is an aldehyde that can be separated from the stem bark of cinnamon. (E) -2-Hydroxycinnamaldehyde inhibits cell proliferation and induces apoptosis by inhibiting signal transduction of STAT3 and reactive oxygen species production. (E) -2-Hydroxycinnamaldehyde has antitumor activity[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319

• Target:

  Apoptosis; Reactive Oxygen Species (ROS) ; STAT

• Type:

  Natural Products

• Related Pathways:

  Apoptosis; Immunology/Inflammation; JAK/STAT Signaling; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/e-2-hydroxycinnamaldehyde.html

• Purity:

  99.83

• Solubility:

  DMSO : 350 mg/mL (ultrasonic)

• Smiles:

  O=C/C=C/C1=C(C=CC=C1)O

• Molecular Formula:

  C9H8O2

• Molecular Weight:

  148.16

• Precautions:

  H315, H319

• References & Citations:

  [1]Yoon YJ, et al. 2'-Hydroxycinnamaldehyde inhibits proliferation and induces apoptosis via signal transducer and activator of transcription 3 inactivation and reactive oxygen species generation. Cancer Sci. 2019 Jan;110 (1) :366-378.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [60125-23-7]