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(E) -2-Hydroxycinnamaldehyde

CAT: 0804-HY-N3149-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3149-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(E) -2-Hydroxycinnamaldehyde is an aldehyde that can be separated from the stem bark of cinnamon. (E) -2-Hydroxycinnamaldehyde inhibits cell proliferation and induces apoptosis by inhibiting signal transduction of STAT3 and reactive oxygen species production. (E) -2-Hydroxycinnamaldehyde has antitumor activity[1].
CAS Number
60125-23-7
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Apoptosis; Reactive Oxygen Species (ROS) ; STAT
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; JAK/STAT Signaling; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-2-hydroxycinnamaldehyde.html
Purity
99.83
Solubility
DMSO : 350 mg/mL (ultrasonic)
Smiles
O=C/C=C/C1=C(C=CC=C1)O
Molecular Formula
C9H8O2
Molecular Weight
148.16
Precautions
H315, H319
References & Citations
[1]Yoon YJ, et al. 2'-Hydroxycinnamaldehyde inhibits proliferation and induces apoptosis via signal transducer and activator of transcription 3 inactivation and reactive oxygen species generation. Cancer Sci. 2019 Jan;110 (1) :366-378.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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