PM-1

CAT: 0804-HY-156404-02Size: 10 mM - 1 mLDry Ice: NoHazardous: No

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CAT#:0804-HY-156404-02Size:10 mM - 1 mL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

PM-1, a derivative of Thioflavin-T (ThT; HY-D0218), is a small but highly specific plasma membrane (PM) fluorescent dye for specific and long-time membrane imaging of living and fixed cells. PM-1 is embedded directly into the cell membrane and exhibits a very long retention time on the plasma membrane with a half-life of approximately 15 h. PM-1 can be used in combination with protein labeling probes to study ectodomain shedding and endocytosis processes of cell surface proteins[1].

CAS Number

1449483-78-6

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pm-1.html

Concentration

10mM

Purity

99.04

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(CCNC1=CC=C(C=C1)C2=NC3=CC=CC=C3S2)=O

Molecular Formula

C16H14N2O2S

Molecular Weight

298.36

References & Citations

[1]Shun-Qiang Xu, et al. Small Plasma Membrane-Targeted Fluorescent Dye for Long-Time Imaging and Protein Degradation Analyses. nal Chem. 2023 Oct 24;95 (42) :15549-15555.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Chemical Information

PM-1

CAS Number	1449483-78-6
PubChem CID	169450730
IUPAC Name	3-[4-(1,3-benzothiazol-2-yl)anilino]propanoic acid
Molecular Formula	C16H14N2O2S
Molecular Weight	298.4
XLogP	4.3
Topological Polar Surface Area	90.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Heavy Atom Count	21
Formal Charge	0
Complexity	358

SMILES

C1=CC=C2C(=C1)N=C(S2)C3=CC=C(C=C3)NCCC(=O)O

InChI

InChI=1S/C16H14N2O2S/c19-15(20)9-10-17-12-7-5-11(6-8-12)16-18-13-3-1-2-4-14(13)21-16/h1-8,17H,9-10H2,(H,19,20)

InChIKey

PWKDNGQJVGZGED-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1449483-78-6

CID: 169450730

Formula: C16H14N2O2S

MW: 298.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	298.4
XLogP3	4.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Exact Mass	298.07759887
Monoisotopic Mass	298.07759887
Topological Polar Surface Area	90.5 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	358
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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HY-177437A	(+) -PM 92131
HY-177020	GS-6620 PM
HY-115231	Ci-IP3/PM
HY-E70621	Sialic acid aldolase (Pm NaNa)
HY-N6838-01	1,1,1,1-Kestohexaose
HY-157129	AMPK-α1β1γ1 activator 1

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Chemical Information

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