PM-1

• UNSPSC Description:

  PM-1, a derivative of Thioflavin-T (ThT; HY-D0218), is a small but highly specific plasma membrane (PM) fluorescent dye for specific and long-time membrane imaging of living and fixed cells. PM-1 is embedded directly into the cell membrane and exhibits a very long retention time on the plasma membrane with a half-life of approximately 15 h. PM-1 can be used in combination with protein labeling probes to study ectodomain shedding and endocytosis processes of cell surface proteins[1].

• Target Antigen:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/pm-1.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  OC(CCNC1=CC=C(C=C1)C2=NC3=CC=CC=C3S2)=O

• Molecular Weight:

  298.36

• References & Citations:

  [1]Shun-Qiang Xu, et al. Small Plasma Membrane-Targeted Fluorescent Dye for Long-Time Imaging and Protein Degradation Analyses. nal Chem. 2023 Oct 24;95(42):15549-15555.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1449483-78-6