PM-43I

• Description :

  PM-43I is a potent STAT6 inhibitor and can reduce STAT6 phosphorylation level. PM-43I can be used in allergic lung disease, allergic rhinitis, chronic pulmonary obstructive disease and cancer research[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  STAT

• Type :

  Reference compound

• Related Pathways :

  JAK/STAT Signaling; Stem Cell/Wnt

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/pm-43i.html

• Purity :

  99.75

• Solubility :

  DMSO : 35 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  CC(C)(C)C(OCOP(C(F)(C1=CC=C(C=C1)/C(C)=C/C(N[C@@H]2C(N(CCCC2)CC(N(C3=CC=CC=C3)C)=O)=O)=O)F)(OCOC(C(C)(C)C)=O)=O)=O

• Molecular Formula :

  C38H50F2N3O10P

• Molecular Weight :

  777.79

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]John S. Mcmurray, et al. Stat6 inhibitors. WO2014182928A2.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1637532-77-4]