PM-43I

• UNSPSC Description:

  PM-43I is a potent STAT6 inhibitor and can reduce STAT6 phosphorylation level. PM-43I can be used in allergic lung disease, allergic rhinitis, chronic pulmonary obstructive disease and cancer research[1].

• Target Antigen:

  STAT

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling;Stem Cell/Wnt

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/pm-43i.html

• Solubility:

  DMSO : 35 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  CC(C)(C)C(OCOP(C(F)(C1=CC=C(C=C1)/C(C)=C/C(N[C@@H]2C(N(CCCC2)CC(N(C3=CC=CC=C3)C)=O)=O)=O)F)(OCOC(C(C)(C)C)=O)=O)=O

• Molecular Weight:

  777.79

• References & Citations:

  [1]John S. Mcmurray, et al. Stat6 inhibitors. WO2014182928A2.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1637532-77-4