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5 (R) -HETE

CAT: 0804-HY-113434A-01Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-113434A-01Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
5 (R) -HETE is a lipoxygenase product of arachidonic acid. 5 (R) -HETE is an inducer of neutrophil migration through endothelial and epithelial barriers. 5 (R) -HETE is important in mediating lung inflammatory processes[1].
CAS Number
61641-47-2
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/5-r-hete.html
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C/C=C\C/C=C\C=C\[C@H](O)CCCC(O)=O
Molecular Formula
C20H32O3
Molecular Weight
320.47
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]D B Bittleman, et al. 5-Hydroxyeicosatetraenoic acid (HETE) -induced neutrophil transcellular migration is dependent upon enantiomeric structure. Am J Respir Cell Mol Biol. 1995 Mar;12 (3) :260-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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