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WDR62 rabbit pAb

CAT: 0855-ES12315-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES12315-01Size:50 µL
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Background
This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]
Description
This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011],
UniProt
O43379
Swiss Prot
O43379
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human WDR62 AA range: 984-1034
Target
WDR62
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Shows cell cycle-dependent localization. Accumulates to the spindle pole during mitosis. Colocalizes with CDK5RAP2, CEP152 and WDR62 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles. .
Gene ID (Human)
284403

UniProtKB · O43379

WD repeat-containing protein 62

WDR62_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O43379
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
WDR62
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q63HP9, Q659D7, Q8NBF7, Q96AD9
Protein keywords

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmCytoskeletonNucleus

Disease

Disease variantIntellectual disabilityPrimary microcephaly

Biological process

Neurogenesis

Technical term

Proteomics identificationReference proteome

Domain

RepeatWD repeat

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