HSD17B13-IN-80-d2

HSD17B13-IN-80-d2

• CAS Number: 2770247-90-8
• UNSPSC Description: HSD17B13-IN-80-d2 (Compound 200) is the the deuterium labeled HSD17B13-IN-80 (HY-163263). HSD17B13-IN-80 is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-80 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
• Target Antigen: 17β-HSD
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Solubility: 10 mM in DMSO
• Smiles: OC1=C(Cl)C=C(C(NC2=C3C(N=C(C)N(C(C4=CC=CC=C4C(F)(F)F)([2H])[2H])C3=O)=C(C)C=C2)=O)C=C1Cl
• Molecular Weight: 538.34
• References & Citations: [1]Sampath Kumar Anandan, et al. Dichlorophenol hsd17b13 inhibitors and uses thereof. WO2022103960A1. 2022-05-19.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported