Catechin

• Description:

  Catechin ((+) -Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.

• Product Name Alternative:

  (+) -Catechin; Cianidanol; Catechuic acid

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319, H335

• Target:

  Apoptosis; COX; Endogenous Metabolite; Influenza Virus

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Catechin.html

• Purity:

  99.57

• Solubility:

  DMSO : 100 mg/mL (ultrasonic) |H2O : 12.5 mg/mL (ultrasonic)

• Smiles:

  O[C@@H]1[C@@H](C2=CC(O)=C(O)C=C2)OC3=CC(O)=CC(O)=C3C1

• Molecular Formula:

  C15H14O6

• Molecular Weight:

  290.27

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40 (2) :173-9.|[2]Alshatwi AA. Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis. J Exp Clin Cancer Res. 2010 Dec 17;29:167.|[3]Cheruku SP, et al. Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats. Cytotechnology. 2018 Feb;70 (1) :245-259.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Natural Products

• Clinical Information:

  Launched

• Isoform:

  COX-1

• Citation 01:

  ACS Omega. 2024 May 17.|Acta Pharm Sin B. 2021 Jan;11 (1) :143-155.|Antioxidants (Basel) . 2024 Jul 28;13 (8) :909.|Biochem Biophys Res Commun. 2018 Sep 3;503 (1) :297-303.|Biochem Biophys Res Commun. 2023 Dec 20:687:149196.|Biomaterials. 2021 Aug:275:120952.|Biomed Chromatogr. 2025 Nov;39 (11) :e70225.|Cancer Rep (Hoboken) . 2025 May;8 (5) :e70169.|Cell Death Dis. 2024 Dec 26;15 (12) :932.|Food Res Int. 2025 Oct:218:116882.|Int J Insect Sci. 2018 Feb 28:10:1179543318758409.|Phytomedicine. 2025 May:140:156549.|Plant Cell Physiol. 2020 Feb 1;61 (2) :318-330.|Plants. 2021 Nov 20;10 (11) :2525.|Rapid Commun Mass Spectrom. 2025 Dec 15;39 (23) :e10134.|SSRN. 2023 Jul 14.|Toxicol Appl Pharmacol. 2024 Jul 14:490:117036.|Autophagy. 2021 Apr;17 (4) :872-887.|Phytomedicine. 2024 May 12:130:155733.

• CAS Number:

  [154-23-4]