Phoenixin-14

• Description:

  Phoenixin-14 (PNX-14) is one of the endogenous active isoform, and generates anxiolytic effect via the activation of the AHA GnRH system in mice. Phoenixin-14 inhibits ischemia/reperfusion-induced cytotoxicity in microglia[1][2].

• Product Name Alternative:

  PNX-14

• UNSPSC:

  12352209

• Target:

  GnRH Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/phoenixin-14.html

• Purity:

  99.16

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C (N[C@@H] (C (C) C) C (N[C@@H] (CCC (N) =O) C (N1[C@@H] (CCC1) C (N2[C@@H] (CCC2) C (NCC (N[C@@H] (CC (C) C) C (N[C@@H] (CCCCN) C (N[C@@H] (C (C) C) C (N[C@@H] (CC3=CNC4=CC=CC=C34) C (N[C@@H] (CO) C (N[C@@H] (CC (O) =O) C (N5[C@@H] (CCC5) C (N[C@@H] (CC6=CC=CC=C6) C (N) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) [C@H] (CC (O) =O) N

• Molecular Formula:

  C75H110N18O20

• Molecular Weight:

  1583.78

• References & Citations:

  [1]Jiang JH, et al. Effects of Phoenixin-14 on anxiolytic-like behavior in mice. Behav Brain Res. 2015;286:39-48.|[2]Ma H, et al. Phoenixin 14 inhibits ischemia/reperfusion-induced cytotoxicity in microglia. Arch Biochem Biophys. 2020;689:108411.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  1415039-79-0