Phoenixin-14 TFA

• Target:

  GNRH Receptor

• Related Pathways:

  GPCR/G Protein

• Purity:

  0.9911

• Bioactivity:

  Phoenixin-14 TFA (PNX-14) is a blood-brain barrier (BBB) -penetrable neuropeptide with anxiolytic, cardioprotective, and neuroprotective properties. It modulates pituitary gonadotrophin release by enhancing gonadotropin-releasing hormone (GnRH) receptor mRNA expression and promotes insulin secretion. Additionally, PNX-14 TFA protects against ischemia/reperfusion (IR) injury in mice and combats oxidative stress by diminishing reactive oxygen species (ROS) and elevating glutathione (GSH) levels [1] [2] [3].

• Smiles:

  [H]N[C@@H] (CC (O) =O) C (N[C@H] (C (N[C@H] (C (N1CCC[C@H]1C (N2CCC[C@H]2C (NCC (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@@H] (CC3=CNC4=C3C=CC=C4) C (N[C@H] (C (N[C@@H] (CC (O) =O) C (N5CCC[C@H]5C (N[C@@H] (CC6=CC=CC=C6) C (N) =O) =O) =O) =O) CO) =O) =O) C (C) C) =O) CCCCN) =O) CC (C) C) =O) =O) =O) =O) CCC (N) =O) =O) C (C) C) =O.OC (C (F) (F) F) =O

• Molecular Formula:

  C75H110N18O20.xC2HF3O2

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C