Lipoxin A5

• UNSPSC Description:

  Lipoxin A5 is an eicosapentaenoic acid derived from pig white blood cells. Lipoxin A5 slowly contracted the guinea pig lung parenchymal strips with a contractile force similar to that of LXA4 and LXB4.2, but LXA5 did not have the vasodilating effect on the aortic smooth muscle shown by LXA4 and LXB4.2[1][2].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/lipoxin-a5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(CCC[C@H](O)[C@H](O)/C=C/C=C/C=C\C=C\[C@@H](O)C/C=C\CC)=O

• Molecular Weight:

  350.45

• References & Citations:

  [1]Wong PY, et al. Lipoxene: a new group of trihydroxy pentaenes of eicosapentaenoic acid derived from porcine leukocytes. Biochem Biophys Res Commun. 1985 Jan 31;126(2):763-72.|[2]Stahl GL, et al. Pharmacologic profile of lipoxins A5 and B5: new biologically active eicosanoids. Eur J Pharmacol. 1989 Apr 12;163(1):55-60.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  110657-98-2