HldA/E-IN-1

HldA/E-IN-1

• CAS Number: 2593325-52-9
• UNSPSC Description: HldA/E-IN-1 (compound 8) is a dual inhibitor of HldA/E, with IC50 values ​​of 17.2 μM and 67.8 μM for HldA/E, respectively. HldA/E-IN-1 can be used in the study of anti-bacterial infection[1].
• Target Antigen: Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/hlda-e-in-1.html
• Smiles: F[C@@H](P(O)(O)=O)[C@@]1(O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H]([C@H](O)COP(O)(O)=O)O1
• Molecular Weight: 402.16
• References & Citations: [1]Cao J, et al. Exploring fluorinated heptose phosphate analogues as inhibitors of HldA and HldE, key enzymes in the biosynthesis of lipopolysaccharide. Bioorg Chem. 2024 Aug 30;153:107767.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported