SNAP 398299

• Description:

  SNAP 398299 is a Gal3 receptor antagonist with potential anxiolytic and antidepressant effects. SNAP 398299 can partially reverse the neuropeptide Galanin-induced inhibition of dorsal raphe cell firing and the Galanin-induced hyperpolarizing current.

• UNSPSC:

  12352005

• Target:

  Galectin

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/snap-398299.html

• Smiles:

  O=C1/C (C2=CC=CC=C2N1C3=CC (OCCN4CCCC4) =CC=C3) =N/C5=CC=CC (C (F) (F) F) =C5

• Molecular Formula:

  C27H24F3N3O2

• Molecular Weight:

  479.49

• References & Citations:

  [1]Insights of structure-based pharmacophore studies and inhibitor design against Gal3 receptor through molecular dynamics simulations|[2]Swanson CJ, et al. Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299. Proc Natl Acad Sci U S A. 2005 Nov 29;102 (48) :17489-94.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  903878-06-8