SNAP 398299

CAT: 0804-HY-123708Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-123708Size:1 Each
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Description
SNAP 398299 is a Gal3 receptor antagonist with potential anxiolytic and antidepressant effects. SNAP 398299 can partially reverse the neuropeptide Galanin-induced inhibition of dorsal raphe cell firing and the Galanin-induced hyperpolarizing current.
CAS Number
[903878-06-8]
UNSPSC
12352005
Target
Galectin
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/snap-398299.html
Smiles
O=C1/C(C2=CC=CC=C2N1C3=CC(OCCN4CCCC4)=CC=C3)=N/C5=CC=CC(C(F)(F)F)=C5
Molecular Formula
C27H24F3N3O2
Molecular Weight
479.49
References & Citations
[1]Insights of structure-based pharmacophore studies and inhibitor design against Gal3 receptor through molecular dynamics simulations|[2]Swanson CJ, et al. Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299. Proc Natl Acad Sci U S A. 2005 Nov 29;102 (48) :17489-94.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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