SNAP 398299

• Description :

  SNAP 398299 is a Gal3 receptor antagonist with potential anxiolytic and antidepressant effects. SNAP 398299 can partially reverse the neuropeptide Galanin-induced inhibition of dorsal raphe cell firing and the Galanin-induced hyperpolarizing current.

• UNSPSC :

  12352005

• Target :

  Galectin

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/snap-398299.html

• Smiles :

  O=C1/C(C2=CC=CC=C2N1C3=CC(OCCN4CCCC4)=CC=C3)=N/C5=CC=CC(C(F)(F)F)=C5

• Molecular Formula :

  C27H24F3N3O2

• Molecular Weight :

  479.49

• References & Citations :

  [1]Insights of structure-based pharmacophore studies and inhibitor design against Gal3 receptor through molecular dynamics simulations|[2]Swanson CJ, et al. Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299. Proc Natl Acad Sci U S A. 2005 Nov 29;102 (48) :17489-94.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [903878-06-8]