SNAP-6201

• Description :

  SNAP-6201 is a selective α1a adrenoceptor antagonist with a Ki of 0.2 nM. SNAP-6201 exhibits >1400-fold selectivity over α1b and α1d adrenoceptors. SNAP-6201 exhibits excellent selectively to inhibit intraurethral pressure (IUP) in the anesthetized dog model. SNAP-6201 can be used for benign prostatic hyperplasia (BPH) research[1].

• UNSPSC :

  12352005

• Target :

  Adrenergic Receptor

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Endocrinology

• Smiles :

  COC(C1(C2=CC=CC=C2)CCN(CCCNC(N3C(NC(CC)=C(C(N)=O)C3C4=CC(F)=C(F)C=C4)=O)=O)CC1)=O

• Molecular Formula :

  C30H35F2N5O5

• Molecular Weight :

  583.63

• References & Citations :

  [1]Nagarathnam D, et al. Design and synthesis of novel alpha (1) (a) adrenoceptor-selective antagonists. 1. Structure-activity relationship in dihydropyrimidinones. J Med Chem. 1999 Nov 18;42 (23) :4764-77.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  α adrenergic receptor

• CAS Number :

  [252201-38-0]