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SNAP-6201

CAT: 0804-HY-W724254Size: 1 EachDry Ice: NoHazardous: No
CAT#: HY-W724254Size: 1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SNAP-6201 is a selective α1a adrenoceptor antagonist with a Ki of 0.2 nM. SNAP-6201 exhibits >1400-fold selectivity over α1b and α1d adrenoceptors. SNAP-6201 exhibits excellent selectively to inhibit intraurethral pressure (IUP) in the anesthetized dog model. SNAP-6201 can be used for benign prostatic hyperplasia (BPH) research[1].
CAS Number
[252201-38-0]
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Endocrinology
Smiles
COC(C1(C2=CC=CC=C2)CCN(CCCNC(N3C(NC(CC)=C(C(N)=O)C3C4=CC(F)=C(F)C=C4)=O)=O)CC1)=O
Molecular Formula
C30H35F2N5O5
Molecular Weight
583.63
References & Citations
[1]Nagarathnam D, et al. Design and synthesis of novel alpha (1) (a) adrenoceptor-selective antagonists. 1. Structure-activity relationship in dihydropyrimidinones. J Med Chem. 1999 Nov 18;42 (23) :4764-77.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α adrenergic receptor

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