Alkyne-SNAP

• Description :

  Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation[1].

• UNSPSC :

  12352005

• Target :

  ADC Linker

• Type :

  Reference compound

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/alkyne-snap.html

• Purity :

  99.32

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(CCC#C)NCC1=CC=C(COC2=NC(N)=NC3=C2NC=N3)C=C1

• Molecular Formula :

  C18H18N6O2

• Molecular Weight :

  350.37

• References & Citations :

  [1]Broichhagen J, et al. Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand. ACS Cent Sci. 2015 Oct 28;1 (7) :383-93.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1104822-07-2]