Alkyne-SNAP

• Description:

  Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation[1].

• UNSPSC:

  12352005

• Target:

  ADC Linker

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/alkyne-snap.html

• Purity:

  99.32

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (CCC#C) NCC1=CC=C (COC2=NC (N) =NC3=C2NC=N3) C=C1

• Molecular Formula:

  C18H18N6O2

• Molecular Weight:

  350.37

• References & Citations:

  [1]Broichhagen J, et al. Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand. ACS Cent Sci. 2015 Oct 28;1 (7) :383-93.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1104822-07-2