Nav1.1 activator 1
CAT:
804-HY-126429-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Nav1.1 activator 1
- CAS Number: 2332897-85-3
- UNSPSC Description: Nav1.1 activator 1 (compound 4), a highly potent Nav1.1 activator with BBB penetration, increases decay time constant (tau) of Nav1.1 currents at 0.03 μM along with significant selectivity against Nav1.2, Nav1.5, and Nav1.6[1].
- Target Antigen: Sodium Channel
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/nav1-1-activator-1.html
- Purity: 99.89
- Solubility: DMSO : 250 mg/mL (ultrasonic)
- Smiles: O=C(C1=C(C2=CC(F)=CC=C2F)C=CN=C1N3C[C@@H](F)CC3)NC4=CC=C(C(C)C)N=C4
- Molecular Weight: 440.46
- References & Citations: [1]Miyazaki T, et al. Discovery of novel 4-phenyl-2-(pyrrolidinyl)nicotinamide derivatives as potent Nav1.1 activators. Bioorg Med Chem Lett. 2019 Mar 15;29(6):815-820.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported