GPER activator 1

• UNSPSC Description:

  GPER activator 1 (compound 6-26) is a GPER-selective compound without cytotoxicity. GPER activator 1 exhibits dual inhibition of TNFα- and IL-6-induced inflammation[1].

• Target Antigen:

  Estrogen Receptor/ERR

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/gper-activator-1.html

• Smiles:

  CC1=C(C(C)=C(C(NC(C2=C(C3=C(S2)C=C(F)C=C3)Cl)=O)=N1)C)O

• Molecular Weight:

  364.82

• References & Citations:

  [1]Bhuwan Prasad Awasthi, et al. G Protein-Coupled Estrogen Receptor-Mediated Anti-Inflammatory and Mucosal Healing Activity of a Trimethylpyridinol Analogue in Inflammatory Bowel Disease. J Med Chem.2024 Jul 11;67(13):10601-10621.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2629960-35-4