[Tyr6,D-Phe7,D-His9]-Substance P (6-11)

• CAS Number:

  145194-26-9

• UNSPSC Description:

  [Tyr6,D-Phe7,D-His9]-Substance P (6-11) is a tachykinin NK1 receptor antagonist that antagonizes Histamine (HY-B1204) induced hyperalgesia[1].

• Target Antigen:

  Neurokinin Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/tyr6-d-phe7-d-his9-substance-p-6-11.html

• Smiles:

  CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CN=CN1)NC([C@@H](NC([C@H](NC([C@@H](N)CC2=CC=C(C=C2)O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)=O

• Molecular Weight:

  856.04

• References & Citations:

  [1]Sakurada, et al. "Possible involvement of tachykinin NK1 and NMDA receptors in histamine-induced hyperalgesia in mice." European journal of pharmacology 434.1-2 (2002): 29-34.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported