[Tyr6,D-Phe7,D-His9]-Substance P (6-11)
CAT:
804-HY-P10619
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
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[Tyr6,D-Phe7,D-His9]-Substance P (6-11)
- CAS Number: 145194-26-9
- UNSPSC Description: [Tyr6,D-Phe7,D-His9]-Substance P (6-11) is a tachykinin NK1 receptor antagonist that antagonizes Histamine (HY-B1204) induced hyperalgesia[1].
- Target Antigen: Neurokinin Receptor
- Type: Peptides
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/tyr6-d-phe7-d-his9-substance-p-6-11.html
- Smiles: CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CN=CN1)NC([C@@H](NC([C@H](NC([C@@H](N)CC2=CC=C(C=C2)O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)=O
- Molecular Weight: 856.04
- References & Citations: [1]Sakurada, et al. "Possible involvement of tachykinin NK1 and NMDA receptors in histamine-induced hyperalgesia in mice." European journal of pharmacology 434.1-2 (2002): 29-34.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported