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CDKN2A Antibody / p16INK4a

CAT: 0800-R20425-0.1MLSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-R20425-0.1MLSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This antibody reacts to human p16INK4a/CDKN2A.
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1:100-1:200, Western blot: 1:1000-1:2000
UniProt
P42771
Host
Rabbit
Reactivity
Human
Immunogen
A peptide corresponding to the C-terminus of human p16INK4a (Cyclin-dependent kinase inhibitor 2A) was used as the immunogen for the recombinant CDKN2A antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
RM409
Type
Recombinant
Applications
WB, IHC-P
Purity
Protein A purified from animal origin-free supernatant
Format
Purified
Buffer
Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide
Reconstitution
Store the recombinant CDKN2A antibody at -20oC.
Limitations
This recombinant CDKN2A antibody is available for research use only.
Storage Conditions
Store the recombinant CDKN2A antibody at -20°C.
Formulation
Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the recombinant CDKN2A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Nucleus, Cytoplasm
Image Legend
Western blot testing of human HEK293 cell lysate with recombinant p16INK4a antibody at 1:2000. Predicted molecular weight ~16 kDa.

UniProtKB · P42771

Cyclin-dependent kinase inhibitor 2A

CDN2A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P42771
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CDKN2A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A5X2G7, D3DRK1, G3XAG3, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Domain

ANK repeatRepeat

Biological process

Cell cycle

Cellular component

CytoplasmNucleus

Disease

Disease variantLi-Fraumeni syndromeTumor suppressor

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