Products for Research Use Only
RegisterLogin

Eletriptan

CAT: 0804-HY-A0039Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-A0039Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Eletriptan (UK-116044) is a highly selective and orally active serotonin 5-HT1B and 5-HT1D receptor agonist, with pKi values of 8.0 and 8.9, respectively. Eletriptan has inhibitory effects on markers of neurogenic inflammation in rats. Eletriptan can be used for researching migraine[1].
CAS Number
143322-58-1
Product Name Alternative
UK-116044
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/eletriptan.html
Solubility
10 mM in DMSO
Smiles
CN1[C@@H](CC2=CNC3=CC=C(CCS(C4=CC=CC=C4)(=O)=O)C=C32)CCC1
Molecular Formula
C22H26N2O2S
Molecular Weight
382.52
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]McCormack PL, Keating GM. Eletriptan: a review of its use in the acute treatment of migraine. Drugs. 2006;66 (8) :1129-49.|[2]Willems E, et al. Porcine carotid vascular effects of eletriptan (UK-116,044) : a new 5-HT1B/1D receptor agonist with anti-migraine activity. Naunyn Schmiedebergs Arch Pharmacol. 1998 Aug;358 (2) :212-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
5-HT1 Receptor; mLAG-3

Alternative Products

CatalogName
MBS5765788Eletriptan
CS-EV-00010Eletriptan-d3
FE38878-01Eletriptan hydrobromide
274912-01Ent-eletriptan
A13075-25Eletriptan 25mg
A13075-10Eletriptan 10mg
B2237-10Eletriptan HBr
448123-01Eletriptan Pseudodimer
A13075-5Eletriptan 5mg

Popular Products