SGLT2-IN-1

CAT: 0804-HY-I1120-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-I1120-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
SGLT2-IN-1 (Compound 5) is an inhibitor for sodium-dependent glucose cotransporter (SGLT2), with IC50 of 33 nM in CHO cells transfected with human SGLT2. SGLT2-IN-1 is selective for SGLT2 over SGLT1. SGLT2-IN-1 is an active metabolite of dapagliflozinactive metabolite of dapagliflozin[1][2].
CAS Number
[864070-37-1]
UNSPSC
12352005
Hazard Statement
H302, H319, H372, H411
Target
SGLT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sglt2-in-1.html
Purity
99.82
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@H](C2=CC(CC3=CC=C(C=C3)O)=C(C=C2)Cl)O[C@@H]([C@H]([C@@H]1O)O)CO
Molecular Formula
C19H21ClO6
Molecular Weight
380.82
Precautions
H302, H319, H372, H411
References & Citations
[1]Lansdell MI, et al., Design and synthesis of fluorescent SGLT2 inhibitors. Bioorg Med Chem Lett. 2008 Sep 15;18 (18) :4944-7. |[2]Xu B, Feng Y, et al. C-aryl glucosides substituted at the 4'-position as potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2011 Aug 1;21 (15) :4465-70.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SGLT2

Related Products

CatalogName
HY-178167SGLT2-IN-3
HY-174400-01SGLT2-IN-2
HY-180201SGLT2-IN-4
HY-138944SGLT1/2-IN-1
HY-112807SGLT inhibitor-1
HY-169821SGLT1/2-IN-8
HY-145357SGLT1/2-IN-2
HY-N6838-011,1,1,1-Kestohexaose
HY-157129AMPK-α1β1γ1 activator 1
HY-1336231,1,1-Tribromoacetone

Alternative Products

CatalogName
BA6945-10SGLT2-IN-1
MBS8581048-01SGLT2 Antibody
MF-0118179-01SGLT2-IN-2
514150SGLT2 discontinued
MBS544463-01SGLT2 Peptide
PVT7137SGLT2 Plasmid
TS424822P5SGLT2 (SLC5A2) CytoSection
SF9015-10mMIpragliflozin (SGLT2 inhibitor)
abx063268-01SGLT2 Blocking Peptide
MBS9233273-01Anti-SGLT2 Antibody

Popular Products