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IACS-9571 (TFA)

CAT: 0804-HY-102000ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-102000ASize:1 Each
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Description
IACS-9571 (trifluoroacetate) is a potent and selective inhibitor of TRIM24 and BRPF1, with IC50 of 8 nM for TRIM24, and Kd of 31 nM and 14 nM for TRIM24 and BRPF1, respectively.
CAS Number
1883598-69-3
Product Name Alternative
ASIS-P040 (TFA)
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/iacs-9571-tfa.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(OC)C(OC)=C1)(NC2=C(OC3=CC(OCCC)=CC(OCCCCN(C)C)=C3)C=C(N4C)C(N(C)C4=O)=C2)=O.FC(F)(C(O)=O)F
Molecular Formula
C34H43F3N4O10S
Molecular Weight
756.79
References & Citations
[1]Palmer WS, et al. Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor. J Med Chem. 2016 Feb 25;59 (4) :1440-54.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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GTR19238427-01IACS-9571 TFA
452138-01IACS-9571
MBS5753298-01IACS-9571 Hydrochloride
A13383-5IACS-9571 5mg
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A13383-25IACS-9571 25mg
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