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IACS-9439

CAT: 0804-HY-153243Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-153243Size:1 Each
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Description
IACS-9439 is a potent, selective, and orally active CSF1R inhibitor with a Ki value of 1 nM inhibitor. IACS-9439 can be used for advanced solid tumors research[1].
CAS Number
2231259-36-0
UNSPSC
12352005
Target
C-Fms
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/iacs-9439.html
Solubility
10 mM in DMSO
Smiles
COC1=C2C(SC(N[C@@H]3[C@H](CCCC3)O)=N2)=CC(OCC4=NC(NC5=CN(N=C5)C)=NC=C4)=C1
Molecular Formula
C23H27N7O3S
Molecular Weight
481.57
References & Citations
[1]Barbara Czako, et al. Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R. J Med Chem. 2020 Sep 10;63 (17) :9888-9911.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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