IACS-9439

• UNSPSC Description:

  IACS-9439 is a potent, selective, and orally active CSF1R inhibitor with a Ki value of 1 nM inhibitor. IACS-9439 can be used for advanced solid tumors research[1].

• Target Antigen:

  c-Fms

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/iacs-9439.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=C2C(SC(N[C@@H]3[C@H](CCCC3)O)=N2)=CC(OCC4=NC(NC5=CN(N=C5)C)=NC=C4)=C1

• Molecular Weight:

  481.57

• References & Citations:

  [1]Barbara Czako, et al. Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R. J Med Chem. 2020 Sep 10;63(17):9888-9911.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2231259-36-0