Products for Research Use Only
RegisterLogin

Dimethyl succinate

CAT: 0804-HY-Y0808-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-Y0808-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Dimethyl succinate is an orally active cell permeable succinate analogue. Dimethyl succinate can disrupt the TCA cycle by elevating intracellular succinate levels, leading to reduced protein synthesis and impairs myogenic differentiation. Dimethyl succinate can induce apoptosis. Dimethyl succinate can decrease maximal cellular respiration and reserve capacity. Dimethyl succinate can rescue synapse loss in AD. Dimethyl succinate can be used for the researches of metabolic and neurological disease[1][2].
CAS Number
106-65-0
UNSPSC
12352200
Hazard Statement
H319, H402
Target
Apoptosis
Type
Biochemical Assay Reagents
Related Pathways
Apoptosis
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dimethyl-succinate.html
Purity
99.95
Solubility
DMSO : 200 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
O=C(OC)CCC(OC)=O
Molecular Formula
C6H10O4
Molecular Weight
146.14
Precautions
H319, H402
References & Citations
[1]Arneson-Wissink PC, et al. The wasting-associated metabolite succinate disrupts myogenesis and impairs skeletal muscle regeneration. JCSM Rapid Commun. 2020;3 (2) :56-69.|[2]Andreyev AY, et al. Metabolic Bypass Rescues Aberrant S-nitrosylation-Induced TCA Cycle Inhibition and Synapse Loss in Alzheimer's Disease Human Neurons. Adv Sci (Weinh) . 2024;11 (12) :e2306469.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

Related Products

CatalogName
HY-150205-01Succinate/succinate receptor antagonist 1
HY-16170Desvenlafaxine (succinate)
HY-135815A-01Mobocertinib (succinate)
HY-B1900-01Methylprednisolone succinate
HY-N0677-01Dehydroandrographolide succinate
HY-B0121-01Sumatriptan succinate
HY-17503A-01Metoprolol (succinate)
HY-109091B-01Lanraplenib (succinate)
HY-A0069-01Doxylamine (succinate)
HY-Y0836-01Diethyl succinate

Alternative Products

CatalogName
13315-32Dimethyl Succinate
TRC-D472816-100MGDimethyl Succinate-d4
D45130-01Dimethyl Succinate 99%
TRC-G399950-1G2-S-Glutathionyl Dimethyl Succinate (Mixture of Diastereomers)
sc-257356Dimethyl succinate-2,2,3,3-d4
TRC-D296501-0.5MG(±)-Desvenlafaxine-d6 Succinate Hydrate (N,N-dimethyl-d6)
CS-C-01281(±) -Desvenlafaxine-d6 Succinate H2O (N, N-dimethyl-d6)

Popular Products