17α-Hydroxyprogesterone acetate

• Description :

  17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate has antiinflammatory effects at the murine maternal-fetal interface[1][2].

• UNSPSC :

  12352211

• Hazard Statement :

  H351

• Target :

  Progesterone Receptor

• Type :

  Reference compound

• Related Pathways :

  Vitamin D Related/Nuclear Receptor

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/17α-hydroxyprogesterone-acetate.html

• Purity :

  99.75

• Solubility :

  DMSO : 5.71 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  CC([C@@]1(OC(C)=O)CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O

• Molecular Formula :

  C23H32O4

• Molecular Weight :

  372.50

• Precautions :

  H351

• References & Citations :

  [1]R E Seegmiller, et al. Evaluation of the teratogenic potential of delalutin (17 alpha-hydroxyprogesterone caproate) in mice. Teratology. 1983 Oct;28 (2) :201-8.|[2]Amy-Eunice Furcron, et al. Vaginal progesterone, but not 17α-hydroxyprogesterone caproate, has antiinflammatory effects at the murine maternal-fetal interface. Am J Obstet Gynecol. 2015 Dec;213 (6) :846.e1-846.e19.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [302-23-8]