17α-Hydroxyprogesterone-d8

• Description:

  17α-Hydroxyprogesterone-d8 is the deuterium labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.

• Product Name Alternative:

  17-Hydroxyprogesterone-d8; 17-OHP-d8

• UNSPSC:

  12352211

• Hazard Statement:

  H225-H301+H311+H331-H370

• Target:

  Endogenous Metabolite; Isotope-Labeled Compounds; Progesterone Receptor

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Others

• Purity:

  99.60

• Solubility:

  DMSO : 50mg/mL (ultrasonic) |H2O : ≥ 0.1mg/mL

• Smiles:

  C[C@@]12[C@](CC[C@]2(O)C(C([2H])([2H])[2H])=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C([2H])([2H])C3)=C([2H])C(C([2H])([2H])C4)=O)C

• Molecular Formula:

  C21H22D8O3

• Molecular Weight:

  338.51

• Precautions:

  P210-P233-P240-P241-P242-P243-P260-P261-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P308+P311-P330-P361+P364-P370+P378-P403+P233-P403+P235-P405-P501

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  850023-80-2