Lactoferrin (17-41) (acetate)

Lactoferrin (17-41) (acetate)

• CAS Number: 2828433-30-1
• UNSPSC Description: Lactoferrin 17-41 (Lactoferricin B) acetate, a peptide corresponding to residues 17-41 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin 17-41 acetate has antitumor activities[1][2].
• Target Antigen: Apoptosis; Bacterial; Fungal
• Type: Peptides
• Related Pathways: Anti-infection;Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer; Infection
• Assay Protocol: https://www.medchemexpress.com/lactoferrin-17-41-acetate.html
• Purity: 99.49
• Solubility: H2O : 25.7 mg/mL (ultrasonic;warming)|DMSO : 20 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C1N[C@@H](CCC(N)=O)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](C)C(N4[C@]([H])(C(N[C@@H](CO)C(N[C@@]([H])([C@H](CC)C)C(N[C@@]([H])([C@@H](C)O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(O)=O)=O)C)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)C(C)C)=O)CSSC[C@H](NC([C@@H](NC([C@H](CC6=CC=CC=C6)N)=O)CCCCN)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H]1CC7=CNC8=CC=CC=C78)=O)=O)=O)=O)=O)=O)=O)CCC4)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C)=O
• Molecular Weight: 3183.82
• References & Citations: [1]Samuelsen Ø, et al. Anti-complement effects of lactoferrin-derived peptides. FEMS Immunol Med Microbiol. 2004 Jun 1;41(2):141-8.|[2]Jiang R, et al. Bovine lactoferrin and lactoferricin exert antitumor activities on human colorectal cancer cells(HT-29) by activating various signaling pathways. Biochem Cell Biol. 2017 Feb;95(1):99-109.|[3]Latorre D, et al. Reciprocal interactions between lactoferrin and bacterial endotoxins and their role in the regulation of the immune response. Toxins (Basel). 2010;2(1):54‐68.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported