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Lactoferrin (17-41) (acetate)

CAT: 0804-HY-P1791B-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1791B-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lactoferrin 17-41 (Lactoferricin B) acetate, a peptide corresponding to residues 17-41 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin 17-41 acetate has antitumor activities[1][2].
CAS Number
2828433-30-1
Product Name Alternative
Lactoferricin B (acetate) ; Lfcin B (acetate)
UNSPSC
12352209
Target
Apoptosis; Bacterial; Fungal
Type
Peptides
Related Pathways
Anti-infection; Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/lactoferrin-17-41-acetate.html
Purity
99.39
Solubility
H2O : 25.7 mg/mL (ultrasonic; warming) |DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1N[C@@H](CCC(N)=O)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](C)C(N4[C@]([H])(C(N[C@@H](CO)C(N[C@@]([H])([C@H](CC)C)C(N[C@@]([H])([C@@H](C)O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(O)=O)=O)C)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)C(C)C)=O)CSSC[C@H](NC([C@@H](NC([C@H](CC6=CC=CC=C6)N)=O)CCCCN)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H]1CC7=CNC8=CC=CC=C78)=O)=O)=O)=O)=O)=O)=O)CCC4)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C)=O
Molecular Formula
C143H226N46O33S3
Molecular Weight
3183.82
References & Citations
[1]Samuelsen Ø, et al. Anti-complement effects of lactoferrin-derived peptides. FEMS Immunol Med Microbiol. 2004 Jun 1;41 (2) :141-8.|[2]Jiang R, et al. Bovine lactoferrin and lactoferricin exert antitumor activities on human colorectal cancer cells (HT-29) by activating various signaling pathways. Biochem Cell Biol. 2017 Feb;95 (1) :99-109.|[3]Latorre D, et al. Reciprocal interactions between lactoferrin and bacterial endotoxins and their role in the regulation of the immune response. Toxins (Basel) . 2010;2 (1) :54‐68.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported

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