Protease-Activated Receptor 4 Agonist

• Description:

  Protease-Activated Receptor 4 Agonist_x000D_ Catalog number: B2012502_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 250 uL_x000D_ Molecular Weight or Concentration: N/A_x000D_ Supplied as: Lyophilized Powder_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: 2-8°C_x000D_ Keywords: PAR4_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Yang J, Mapelli C, Wang Z, Sum CS, Hua J, Lawrence RM, Ni Y, Seiffert DA. An optimized agonist peptide of protease-activated receptor 4 and its use in a validated platelet-aggregation assay Platelets. 2022 Oct 3;33(7):979-986._x000D_ 2: Fu Q, Cheng J, Gao Y, Zhang Y, Chen X, Xie J. Protease-activated receptor 4: a critical participator in inflammatory response Inflammation. 2015 Apr;38(2):886-95._x000D_ 3: Rigg RA, Healy LD, Chu TT, Ngo ATP, Mitrugno A, Zilberman-Rudenko J, Aslan JE, Hinds MT, Vecchiarelli LD, Morgan TK, Gruber A, Temple KJ, Lindsley CW, Duvernay MT, Hamm HE, McCarty OJT. Protease-activated receptor 4 activity promotes platelet granule release and platelet-leukocyte interactions Platelets. 2019;30(1):126-135._x000D_ 4: Smith TH, Coronel LJ, Li JG, Dores MR, Nieman MT, Trejo J. Protease-activated Receptor-4 Signaling and Trafficking Is Regulated by the Clathrin Adaptor Protein Complex-2 Independent of β-Arrestins J Biol Chem. 2016 Aug 26;291(35):18453-64._x000D_ 5: Barra A, Freitas KM, Marconato DG, Faria-Pinto P, Lopes MTP, Klein A. Protease-activated receptor 4 plays a role in lipopolysaccharide-induced inflammatory mechanisms in murine macrophages Naunyn Schmiedebergs Arch Pharmacol. 2021 May;394(5):853-862._x000D_ 6: Kolpakov MA, Rafiq K, Guo X, Hooshdaran B, Wang T, Vlasenko L, Bashkirova YV, Zhang X, Chen X, Iftikhar S, Libonati JR, Kunapuli SP, Sabri A. Protease-activated receptor 4 deficiency offers cardioprotection after acute ischemia reperfusion injury J Mol Cell Cardiol. 2016 Jan;90:21-9._x000D_ 7: Augé C, Balz-Hara D, Steinhoff M, Vergnolle N, Cenac N. Protease-activated receptor-4 (PAR 4): a role as inhibitor of visceral pain and hypersensitivity Neurogastroenterol Motil. 2009 Nov;21(11):1189-e107._x000D_ 8: Wadowski PP, Pultar J, Weikert C, Eichelberger B, Panzer B, Huber K, Lang IM, Koppensteiner R, Panzer S, Gremmel T. Protease-activated receptor-mediated platelet aggregation in acute coronary syndrome patients on potent P2Y(12) inhibitors Res Pract Thromb Haemost. 2019 May 22;3(3):383-390._x000D_ 9: Chandrabalan A, Ramachandran R. Molecular mechanisms regulating Proteinase-Activated Receptors (PARs) FEBS J. 2021 Apr;288(8):2697-2726._x000D_ 10: Sabri A, Guo J, Elouardighi H, Darrow AL, Andrade-Gordon P, Steinberg SF. Mechanisms of protease-activated receptor-4 actions in cardiomyocytes. Role of Src tyrosine kinase J Biol Chem. 2003 Mar 28;278(13):11714-20. _x000D_ _x000D_ Products Related to Protease-Activated Receptor 4 Agonist can be found at Chemicals

• Short Description:

  Catalog Number: B2012502 (250 uL)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5