Protease-Activated Receptor-1, PAR-1 Agonist (TFA)

Protease-Activated Receptor-1, PAR-1 Agonist (TFA)

• UNSPSC Description: Protease-Activated Receptor-1, PAR-1 Agonist TFA is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist TFA corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor[1][2].
• Target Antigen: Protease Activated Receptor (PAR)
• Type: Peptides
• Related Pathways: GPCR/G Protein
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protease-activated-receptor-1-par-1-agonist-tfa.html
• Purity: 98.54
• Solubility: H2O : 6.67 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C([C@@H](N)[C@@H](C)O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC(N)=O)=O)CCCNC(N)=N)=O)CC(C)C)=O)CC(C)C)=O)CC1=CC=CC=C1.OC(C(F)(F)F)=O
• Molecular Weight: 876.92
• References & Citations: [1]Heider I, et al. PAR1-type thrombin receptor stimulates migration and matrix adhesion of human colon carcinoma cells by a PKCepsilon-dependent mechanism. Oncol Res. 2004;14(10):475-482.|[2]Stefanie Gödecke, et al. Thrombin-induced ATP release from human umbilical vein endothelial cells. Am J Physiol Cell Physiol. 2012 Mar 15;302(6):C915-23.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported