FGFR2-IN-2

FGFR2-IN-2

• CAS Number: 2677709-81-6
• UNSPSC Description: FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively[1].
• Target Antigen: FGFR
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/fgfr2-in-2.html
• Solubility: DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: OC1=CC=C(C2=CC3=C(C(C4=CC=C(N5CCNCC5)C=C4)=NN3)C=C2)C=C1
• Molecular Weight: 370.45
• References & Citations: [1]Lewis D Turner, et al. From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. J Med Chem. 2022 Jan 27;65(2):1481-1504.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported