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FGFR2/3-IN-2

CAT: 0013-GTR19249073-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249073-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGFR2/3-IN-2 is a potent and selective oral inhibitor of FGFR2 (IC50=3.7 nM) and FGFR3 (IC50=31.2 nM) . It demonstrates antitumor efficacy, including stasis and regression, in models like SNU-16 gastric cancer, without inducing common on-target toxicities such as hyperphosphatemia or diarrhea in vivo.
CAS Number
3025799-28-1
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C (N) C1=C2C=NC (=CN2C (C=3C=CC (=CC3) NC (=O) C (F) =C) =C1C4=CC=C (OC5=NC=CC (=N5) C) C=C4) C
Molecular Formula
C29H23FN6O3
Molecular Weight
522.53
Storage Conditions
-20°C
Notes
For research use only.

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