Gabapentin (Standard)

• Description :

  Gabapentin (Standard) is the analytical standard of Gabapentin. This product is intended for research and analytical applications. Gabapentin is a potent, orally active P/Q type Ca2+ channel blocker. Gabapentin inhibits neuronal Ca2+ influx and reduction of neurotransmitter release. Gabapentin is a GABA analog that can be used to relieve neuropathic pain[1][2][3].

• UNSPSC :

  12352211

• Hazard Statement :

  H315-H319-H335-H360

• Target :

  Calcium Channel; Reference Standards

• Type :

  Reference Standards

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling; Others

• Field of Research :

  Neurological Disease; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/gabapentin-standard.html

• Smiles :

  O=C(O)CC1(CN)CCCCC1

• Molecular Formula :

  C9H17NO2

• Molecular Weight :

  171.24

• Precautions :

  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Fink K, et, al. Inhibition of neuronal Ca (2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices. Br J Pharmacol. 2000 Jun;130 (4) :900-6.|[2]Celikyurt IK, et, al. Gabapentin, A GABA analogue, enhances cognitive performance in mice. Neurosci Lett. 2011 Apr 1;492 (2) :124-8.|[3]Meymandi MS, et, al. Gabapentin action and interaction on the antinociceptive effect of morphine on visceral pain in mice. Eur J Anaesthesiol. 2008 Feb;25 (2) :129-34.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [60142-96-3]