Gabapentin (Standard)

Gabapentin (Standard)

• CAS Number: 60142-96-3
• UNSPSC Description: Gabapentin (Standard) is the analytical standard of Gabapentin. This product is intended for research and analytical applications. Gabapentin is a potent, orally active P/Q type Ca2+ channel blocker. Gabapentin inhibits neuronal Ca2+ influx and reduction of neurotransmitter release. Gabapentin is a GABA analog that can be used to relieve neuropathic pain[1][2][3].
• Target Antigen: Calcium Channel
• Type: Reference Standards
• Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
• Field of Research: Neurological Disease; Cancer
• Assay Protocol: https://www.medchemexpress.com/gabapentin-standard.html
• Smiles: O=C(O)CC1(CN)CCCCC1
• Molecular Weight: 171.24
• References & Citations: [1]Fink K, et, al. Inhibition of neuronal Ca(2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices. Br J Pharmacol. 2000 Jun;130(4):900-6.|[2]Celikyurt IK, et, al. Gabapentin, A GABA analogue, enhances cognitive performance in mice. Neurosci Lett. 2011 Apr 1;492(2):124-8.|[3]Meymandi MS, et, al. Gabapentin action and interaction on the antinociceptive effect of morphine on visceral pain in mice. Eur J Anaesthesiol. 2008 Feb;25(2):129-34.
• Shipping Conditions: Room temperature