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Gabapentin-d6 (hydrochloride)

CAT: 0804-HY-A0057ASSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-A0057ASSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gabapentin-d6 (hydrochloride) is deuterium labeled Gabapentin (hydrochloride) .
CAS Number
1432061-73-8
UNSPSC
12352211
Target
Calcium Channel; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
OC(CC1(CC([2H])([2H])C([2H])([2H])C([2H])([2H])C1)CN)=O.Cl
Molecular Formula
C9H12D6ClNO2
Molecular Weight
213.73
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Harden RN, et al. A Phase 2a, Randomized, Crossover Trial of Gabapentin Enacarbil for the Treatment of Postherpetic Neuralgia inGabapentin Inadequate Responders. Pain Med. 2013 Sep 18.|[3]Lee BS, et al. Intrathecal gabapentin increases interleukin-10 expression and inhibits pro-inflammatory cytokine in a rat model of neuropathic pain. J Korean Med Sci. 2013 Feb;28 (2) :308-14.|[4]Parker DA, et al. Gabapentin activates presynaptic GABAB heteroreceptors in rat cortical slices. Eur J Pharmacol. 2004 Jul 14;495 (2-3) :137-43.|[5]Receveur JM, et al. Synthesis and biological evaluation of conformationally restricted Gabapentin analogues. Bioorg Med Chem Lett. 1999 Aug 16;9 (16) :2329-34.|[6]Stefani A, et al. Gabapentin inhibits calcium currents in isolated rat brain neurons. Neuropharmacology. 1998;37 (1) :83-91.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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HHC06173-01Gabapentin-d6 hydrochloride
CS-T-55148Gabapentin Hydrochloride-d6, d7 [d6 Major]
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CS-O-15443Gabapentin-d4 Hydrochloride
A10414-10Gabapentin Hydrochloride 10mg
A10414-200Gabapentin Hydrochloride 200mg
A10414-50Gabapentin Hydrochloride 50mg
A10414-100Gabapentin Hydrochloride 100mg
A10414-500Gabapentin Hydrochloride 500mg
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