Products for Research Use Only
RegisterLogin

MS4078

CAT: 0804-HY-112155-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-112155-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MS4078 is an anaplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19 nM for binding affinity to ALK[1].
CAS Number
2229036-62-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Anaplastic lymphoma kinase (ALK) ; PROTACs
Type
Reference compound
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MS4078.html
Purity
99.72
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC(C)S(C1=C(NC2=NC(NC3=C(OC(C)C)C=C(C4CCN(CC(NCCNC5=C(C(N(C6C(NC(CC6)=O)=O)C7=O)=O)C7=CC=C5)=O)CC4)C(C)=C3)=NC=C2Cl)C=CC=C1)(=O)=O
Molecular Formula
C45H52ClN9O8S
Molecular Weight
914.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang C, et al. Proteolysis Targeting Chimeras (PROTACs) of Anaplastic Lymphoma Kinase (ALK) . Eur J Med Chem. 2018 May 10;151:304-314.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

Related Products

CatalogName
HY-112156-01MS4077
HY-176035MS479
HY-114994-01MS437
HY-120000-01MS402
HY-114918-01MS438
HY-111139-01MS417
HY-148829MS40
HY-RS08705MS4A7 Human Pre-designed siRNA Set A
HY-RS16475MS4A8 Human Pre-designed siRNA Set A
HY-RS21656Ms4a7 Mouse Pre-designed siRNA Set A

Alternative Products

CatalogName
BA8782-5MS4078
A20089-2MS4078 2mg
A20089-1MS4078 1mg
A20089-25MS4078 25mg
A20089-5MS4078 5mg

Popular Products