MS417

CAT: 0804-HY-111139-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-111139-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
MS417 is a selective BET-specific BRD4 inhibitor, binds to BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively, with weak selectivity at CBP BRD (IC50, 32.7 μM) .
CAS Number
[916489-36-6]
Product Name Alternative
GTPL7512
UNSPSC
12352005
Target
Epigenetic Reader Domain; HIV
Type
Reference compound
Related Pathways
Anti-infection; Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/MS417.html
Purity
99.79
Solubility
10 mM in DMSO|Ethanol : 50 mg/mL (ultrasonic)
Smiles
O=C(OC)C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C)S3)C(C4=CC=C(Cl)C=C4)=N1
Molecular Formula
C20H19ClN4O2S
Molecular Weight
414.91
References & Citations
[1]Zhang G, et al. Down-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibition. J Biol Chem. 2012 Aug 17;287 (34) :28840-51.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-114994-01MS437
HY-169093-01MS41
HY-RS08705MS4A7 Human Pre-designed siRNA Set A
HY-RS21656Ms4a7 Mouse Pre-designed siRNA Set A
HY-RS28174Ms4a7 Rat Pre-designed siRNA Set A

Alternative Products

CatalogName
MBS5755233MS417
A19433-500MS417 500mg
A19433-5MS417 5mg
A19433-100MS417 100mg
A19433-1MS417 1mg
A19433-2MS417 2mg
A19433-10MS417 10mg
A19433-25MS417 25mg
A19433-50MS417 50mg

Popular Products