Moxonidine-13C,d3 (hydrochloride)
CAT:
804-HY-B0374AS
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Moxonidine-13C,d3 (hydrochloride)
- UNSPSC Description: Moxonidine-13C,d3 hydrochloride is 13C and deuterated labeled Moxonidine hydrochloride (HY-B0374A). Moxonidine (BDF5895) hydrochloride is an imidazoline type 1 receptor (I1-R) selective agonist and antihypertensive agent.
- Target Antigen: Imidazoline Receptor; Isotope-Labeled Compounds
- Type: Isotope-Labeled Compounds
- Related Pathways: Neuronal Signaling;Others
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Solubility: 10 mM in DMSO
- Smiles: CC1=NC(Cl)=C(C(O[13C]([2H])([2H])[2H])=N1)NC2=NCCN2.Cl
- Molecular Weight: 282.15
- References & Citations: [1]Schafer, U., et al., Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors. J Pharmacol Exp Ther, 2002. 303(3): p. 1163-70.|[2]Chan, C.K., et al., Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine. Neuroscience, 2005. 132(4): p. 991-1007.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported