Cyclobenzaprine-13C,d3 (hydrochloride)

Cyclobenzaprine-13C,d3 (hydrochloride)

• CAS Number: 1261394-10-8
• UNSPSC Description: Cyclobenzaprine-13C,d3 (hydrochloride) is the 13C- and deuterium labeled Cyclobenzaprine (hydrochloride).
• Target Antigen: 5-HT Receptor; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: GPCR/G Protein;Neuronal Signaling;Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Solubility: 10 mM in DMSO
• Smiles: [2H][13C]([2H])([2H])N(C)CC/C=C1C2=CC=CC=C2C=CC3=CC=CC=C3/1.Cl
• Molecular Weight: 315.86
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.|[2]Honda, M., T. Nishida, and H. Ono, Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT(2) receptors. Eur J Pharmacol, 2003. 458(1-2): p. 91-9.|[3]Kobayashi, H., Y. Hasegawa, and H. Ono, Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems. Eur J Pharmacol, 1996. 311(1): p. 29-35.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported