β-Pompilidotoxin (TFA)

• UNSPSC Description:

  β-Pompilidotoxin TFA (β-PMTX TFA), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells[1].

• Target Antigen:

  Sodium Channel

• Type:

  Peptides

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/β-pompilidotoxin-tfa.html

• Solubility:

  H2O

• Smiles:

  OC(C(F)(F)F)=O.CC(C)C[C@@H](C(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CC(C)C)NC(CNC([C@H]([C@@H](C)CC)NC([C@H](CCCCN)NC([C@H]([C@@H](C)CC)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  1671.90

• References & Citations:

  [1]Tina M Grieco, et al. Production of resurgent current in NaV1.6-null Purkinje neurons by slowing sodium channel inactivation with beta-pompilidotoxin. J Neurosci. 2004 Jan 7;24(1):35-42.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported