β-Pompilidotoxin

• UNSPSC Description:

  β-Pompilidotoxin (β-PMTX), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells[1].

• Target Antigen:

  Sodium Channel

• Type:

  Peptides

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/β-pompilidotoxin.html

• Purity:

  97.12

• Solubility:

  H2O : ≥ 100 mg/mL

• Smiles:

  [C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CCCNC(=N)N)=O)CO)=O)CC(C)C)=O)CCC(N)=O)=O)CC(O)=O)=O)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)[C@H](CC)C)=O)CCCCN)=O)[C@H](CC)C)=O)=O)CC(C)C)=O

• Molecular Weight:

  1557.88

• References & Citations:

  [1]Tina M Grieco, et al. Production of resurgent current in NaV1.6-null Purkinje neurons by slowing sodium channel inactivation with beta-pompilidotoxin. J Neurosci. 2004 Jan 7;24(1):35-42.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported

• CAS Number:

  216064-36-7