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SCH 486757

CAT: 0804-HY-19467-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-19467-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SCH 486757 is an orally effective pain peptide receptor (NOP) agonist. SCH 486757 can be used for the study of cough[1].
CAS Number
524019-25-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sch-486757.html
Solubility
10 mM in DMSO
Smiles
ClC1=C(C=CC=C1)C(C(C=CC=C2)=C2Cl)N([C@H]3C4)[C@@H](CC3)C[C@@]4(C5=NC=CC=N5)O
Molecular Formula
C24H23Cl2N3O
Molecular Weight
440.36
Precautions
P261-P280-P302+P352
References & Citations
[1]McLeod RL, et al. Pharmacological profile of the NOP agonist and cough suppressing agent SCH 486757 (8-[Bis (2-Chlorophenyl) Methyl]-3- (2-Pyrimidinyl) -8-Azabicyclo[3.2.1]Octan-3-Ol) in preclinical models. Eur J Pharmacol. 2010 Mar 25;630 (1-3) :112-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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