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S-Propargylcysteine

CAT: 0804-HY-W001538-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W001538-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H2S-releasing compound. S-Propargylcysteine reduces Ca2+ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties[1][2].
CAS Number
3262-64-4
Product Name Alternative
SPRC
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
MDM-2/p53; STAT
Type
Reference compound
Related Pathways
Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/s-propargylcysteine.html
Purity
97.0
Solubility
H2O : 25 mg/mL (ultrasonic)
Smiles
O=C([C@H](CSCC#C)N)O
Molecular Formula
C6H9NO2S
Molecular Weight
159.21
Precautions
H302, H315, H319, H335
References & Citations
[1]Sidhapuriwala JN, et al. Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice. PLoS One. 2012;7 (3) :e32574.|[2]Wen YD, et al. The Pharmacological Effects of S-Propargyl-Cysteine, a Novel Endogenous H2S-Producing Compound. Handb Exp Pharmacol. 2015;230:325-36.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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