D-JBD19 (TFA)

• Description:

  D-JBD19 TFA is a non-permeable peptide[1]. D-JBD19 TFA has neuroprotective effects[2].

• UNSPSC:

  12352209

• Target:

  JNK

• Type:

  Peptides

• Related Pathways:

  MAPK/ERK Pathway

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/d-jbd19-tfa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N=C (N) NCCC[C@H] (C (O) =O) NC ([C@@H]1N (C ([C@@H] (CCCCN) NC ([C@@H] (CCCNC (N) =N) NC ([C@@H]2N (C ([C@@H] ([C@@H] (O) C) NC ([C@@H] ([C@@H] (O) C) NC ([C@@H] (CC (C) C) NC ([C@@H] (CC (N) =O) NC ([C@@H] (CC (C) C) NC ([C@@H] (CC3=CC=CC=C3) NC ([C@@H]4N (C ([C@@H] (CCC (N) =O) NC ([C@@H] (C (C) C) NC ([C@@H]5N (C ([C@@H] (CCCNC (N) =N) NC ([C@@H] (CO) NC ([C@@H] (CCC (N) =O) NC ([C@@H] (CC (O) =O) N) =O) =O) =O) =O) CCC5) =O) =O) =O) CCC4) =O) =O) =O) =O) =O) =O) =O) CCC2) =O) =O) =O) CCC1) =O.OC (C (F) (F) F) =O

• Molecular Formula:

  C101H165F3N32O30

• Molecular Weight:

  2364.58

• References & Citations:

  [1]Cardozo AK, et al. Cell-permeable peptides induce dose- and length-dependent cytotoxic effects. Biochim Biophys Acta. 2007 Sep;1768 (9) :2222-34.|[2]Vaslin A, et al. Excitotoxicity-induced endocytosis mediates neuroprotection by TAT-peptide-linked JNK inhibitor. J Neurochem. 2011 Dec;119 (6) :1243-52.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported