D-JBD19

• Description :

  D-JBD19 is an impermeable peptide that serves as an inactive control for the JNK inhibitor D-JNKI1 (HY-P0069) . D-JNKI1 has neuroprotective effects[1][2].

• CAS Number :

  [954134-42-0]

• UNSPSC :

  12352209

• Target :

  JNK

• Type :

  Peptides

• Related Pathways :

  MAPK/ERK Pathway

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/d-jbd19.html

• Purity :

  99.84

• Solubility :

  10 mM in DMSO

• Smiles :

  N=C(N)NCCC[C@H](C(O)=O)NC([C@@H]1N(C([C@@H](CCCCN)NC([C@@H](CCCNC(N)=N)NC([C@@H]2N(C([C@@H]([C@@H](O)C)NC([C@@H]([C@@H](O)C)NC([C@@H](CC(C)C)NC([C@@H](CC(N)=O)NC([C@@H](CC(C)C)NC([C@@H](CC3=CC=CC=C3)NC([C@@H]4N(C([C@@H](CCC(N)=O)NC([C@@H](C(C)C)NC([C@@H]5N(C([C@@H](CCCNC(N)=N)NC([C@@H](CO)NC([C@@H](CCC(N)=O)NC([C@@H](CC(O)=O)N)=O)=O)=O)=O)CCC5)=O)=O)=O)CCC4)=O)=O)=O)=O)=O)=O)=O)CCC2)=O)=O)=O)CCC1)=O

• Molecular Formula :

  C99H164N32O28

• Molecular Weight :

  2250.56

• References & Citations :

  [1]Cardozo AK, et al. Cell-permeable peptides induce dose- and length-dependent cytotoxic effects. Biochim Biophys Acta. 2007 Sep;1768 (9) :2222-34.|[2]Vaslin A, et al. Excitotoxicity-induced endocytosis mediates neuroprotection by TAT-peptide-linked JNK inhibitor. J Neurochem. 2011 Dec;119 (6) :1243-52.|[3]Vaslin A, et al. Excitotoxicity-induced endocytosis mediates neuroprotection by TAT-peptide-linked JNK inhibitor. J Neurochem. 2011 Dec;119 (6) :1243-52.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported