cis-4-Hydroxy-L-proline (hydrochloride)

CAT:

804-HY-W019213-02

Size:

10 g

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CAS Number: 441067-49-8
UNSPSC Description: cis-4-Hydroxy-L-proline hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). cis-4-Hydroxy-L-proline hydrochloride is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Target Antigen: ADC Linker; PROTAC Linkers
Type: ADC Related
Related Pathways: Antibody-drug Conjugate/ADC Related;PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/cis-4-hydroxy-l-proline-hydrochloride.html
Purity: 97.0
Solubility: 10 mM in DMSO
Smiles: [H]Cl.O=C(O)[C@H]1NC[C@@H](O)C1
Molecular Weight: 167.59
References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
Shipping Conditions: Room Temperature
Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information: No Development Reported

Cat	Name
HY-W019213-02	cis-4-Hydroxy-L-proline (hydrochloride)
HY-W019213-01	cis-4-Hydroxy-L-proline (hydrochloride)
HY-40136-01	cis-4-Hydroxy-L-proline
HY-40136-02	cis-4-Hydroxy-L-proline
HY-40136R	cis-4-Hydroxy-L-proline (Standard)
HY-40136S	cis-4-Hydroxy-L-proline-d3
HY-W002886-01	N-Boc-cis-4-hydroxy-L-proline
HY-W002886-02	N-Boc-cis-4-hydroxy-L-proline
HY-W002887-02	N-Boc-cis-4-Hydroxy-D-proline
HY-W002887-01	N-Boc-cis-4-Hydroxy-D-proline

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