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DOTAGA. (SA.FAPi) 2 (TFA)

CAT: 0804-HY-164364A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-164364A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DOTAGA. (SA.FAPi) 2 TFA is a potent dimeric fibroblast-activation protein inhibitor (FAPi) . DOTAGA. (SA.FAPi) 2 TFA has the potential for cancer diagnosis research[1].
UNSPSC
12352005
Target
FAP
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dotaga-sa-fapi-2-tfa.html
Purity
97.51
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(O)CN1CCN(C(CCC(NCCNC(C2=O)=C(NCCCCOC3=CC4=C(N=CC=C4C(NCC(N5[C@H](C#N)CC(C5)(F)F)=O)=O)C=C3)C2=O)=O)C(O)=O)CCN(CCN(CC1)CCNC(C6=O)=C(NCCCCOC7=CC8=C(N=CC=C8C(NCC(N9[C@H](C#N)CC(C9)(F)F)=O)=O)C=C7)C6=O)CC(O)=O.OC(C(F)(F)F)=O
Molecular Formula
C73H84F7N17O19
Molecular Weight
1636.54
References & Citations
[1]Tilman Läppchen, et al. Tailoring Fibroblast-Activation Protein Targeting for Theranostics: A Comparative Preclinical Evaluation of the 68Ga- and 177Lu-Labeled Monomeric and Dimeric Fibroblast-Activation Protein Inhibitors DOTA.SA.FAPi and DOTAGA. (SA.FAPi) 2. Molecules. 2024 Jun 28;29 (13) :3093.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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